• br In December consecutive waves of major smog shrouded

  2019-06-10

  

  In December, 2016, consecutive waves of major smog shrouded China, particularly the North China Plain and Sichuan Basin, resulting in suspended schools, halted industrial production, and heavy traffic. Atmospheric levels of fine particulate Cy3.5 maleimide (PM) spiked to more than 500 μg/m in Hena

• br Since the launch of the

  2019-06-10

  

  Since the launch of the Every Newborn Action Plan (ENAP) at the World Health Assembly in 2014, and, in 2015, the launch of the UN Secretary General\'s second Global Strategy for Women\'s, Children\'s and Adolescents\' Health, there has been a renewed focus on improving newborn health globally. So

• br Cholera remains a serious global public health problem di

  2019-06-10

  

  Cholera remains a serious global public health problem, disproportionately affecting poor individuals, causing illness and death for thousands of people each year. Cholera cases are on the rise, with 47% more cases reported to WHO in 2014 than in 2013. Innovative approaches to control the disease

• Heart failure is a complex disease and the status

  2019-06-10

  

  Heart failure is a complex disease and the status of each patient is highly heterogeneous; therefore, nominal manufacturer-delivered device settings may not be optimal for all patients who receive CRT implantation. A growing body of evidence suggests hemodynamic and clinical status benefits associat

• In another study Lopez and associates

  2019-06-10

  

  In another study Lopez and associates found that patients with chronic heart failure receiving torsemide, a loop diuretic that inhibits the enzyme involved in the myocardial extracellular generation of collagen type I molecules (i.e., procollagen type I carboxy-terminal proteinase or PCP), had reduc

• Introduction Hepatosplenic T cell lymphoma

  2019-06-06

  

  Introduction Hepatosplenic T-cell lymphoma (HSTCL) is a rare subtype of peripheral T-cell lymphoma, which is derived from cytotoxic T-cells typically expressing γδ T-cell receptor (TCR). It usually occurs in young men and is characterized by B symptoms such as a fever, weight loss and night sweats,

• The WHO guidance promotes pre exposure prophylaxis for all

  2019-06-06

  

  The 2016 WHO guidance promotes pre-exposure prophylaxis for all populations with an incidence of HIV above three per 100 person-years. This guidance is, some ways, an indictment on the promotion of condoms in HIV prevention. However, WHO does not retract its message regarding the use of condoms. The

• Although the CHADS score is useful for

  2019-06-06

  

  Although the CHADS2 score is useful for evaluating the risk of stroke in NVAF patients, about half of all NVAF patients have a score of 0 or 1 [7]. There are no clear guidelines on whether warfarin should be administered or not, to these patients because the risk of annual incidence of stroke is so

• br Postoperative rehabilitation Although surgery is

  2019-06-06

  

  Postoperative rehabilitation Although surgery is the main curative therapy for lung cancer, the procedure can directly cause a reduction in pulmonary functional reserve and exercise capacity proportional to the extent of resection. The problems might be more severe in those undergoing multimodali

• br It is encouraging to read

  2019-06-06

  

  It is encouraging to read in the Article by Mercy Kanyuka and colleagues (March, 2016) about Malawi\'s success in reducing child mortality, but I fear the authors might have missed one of the key factors contributing towards this great achievement. Specifically, that Malawi is unique in sub-Sahara

• Changing the pacemaker mode to VDD is a good

  2019-06-06

  

  Changing the pacemaker mode to VDD is a good approach in cases of normal sinus node function and loss of atrial lead capture, especially if atrial sensing is stable. In this case, Short AV delay is a good way to reduce the risk of R on T phenomenon which is theoretically possible if a ventricular ec

• br Discussion Zoledronic acid has been

  2019-06-05

  

  Discussion Zoledronic 69 9 has been approved for prevention and treatment of osteoporosis and glucocorticoids-induced osteoporosis, treatment of Paget\'s disease, hypercalcemia, multiple myeloma and bone metastasis. In the particular case of breast cancer, it is recommended as a monthly administr

• smad We conducted a retrospective analysis to compare

  2019-06-05

  

  We conducted a retrospective analysis to compare a BMD-alone strategy, versus BMD+FRAX® and BMD+FRAX®+TBS screening strategies. To our knowledge, this constitutes the first study to assess the relative contributions of FRAX® and TBS. In our cohort, FRAX®+BMD identified 9 (9%) additional patients at

• After overdrive pacing excitation that

  2019-06-05

  

  After overdrive pacing, excitation that is one lap behind (the second beat after the stimulus) is caused by several mechanisms. One is the prolonged conduction time that is longer than the TCL due to a long conduction pathway and/or slow conduction. The other is the dual-loop reentry [12]. The excit

• Human ether a go go

  2019-06-05

  

  Human-ether-a-go-go-related gene (HERG) encodes the α-subunit of rapidly-activating delayed-rectifier potassium mu receptor that generate IKr. This outward potassium current is elicited during the plateau phase of action potentials and is required for repolarization [4]. After being translated in t

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