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Chronic hepatitis B virus HBV
2019-04-23
Chronic carboxypeptidase a virus (HBV) infection is prevalent in many Asian countries, notwithstanding three decades of universal hepatitis B vaccination programs. The invention of nucleos(t)ide analogs (NUCs) was a breakthrough in the treatment of chronic hepatitis B (CHB). However, HBV continues t
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SQTS is relatively rare but should be
2019-04-23
SQTS is relatively rare, but should be considered if the QT interval is markedly abbreviated and the ST segment is nearly absent with peaked and symmetrical T waves. Thus far, mutations in 5 different genes have been found, but genetic testing remains investigational because these genes account for
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Osteoporosis was defined as BMD standard deviations or more
2019-04-23
Osteoporosis was defined as BMD 2.5 standard deviations or more below the reference range mean for young adults. Osteopaenia being those with a BMD between 1 and 2.5 standard deviations below the young adult mean [7]. Lumbar spine (L2-L4) and femoral neck BMD was quantified with Lunar DPX-L (Lunar,
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Effect of atorvastatin in modulation
2019-04-23
Effect of atorvastatin in modulation and protection of cardiomyocyte ischemia and inflammatory phenomena (identified as a decline in perioperative CRP, hs-cTnT, and CPK-MB levels) [15,25–27] was not confirmed in the PROFACE trial. Because of no significant differences in the clinical preoperative or
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Los tres aspectos se alados del marco paratextual se
2019-04-23
Los tres aspectos señalados del marco paratextual se encuentran ligados smad pathway las condiciones de producción y de publicación de la novela y allanan el camino de la apropiación y de la subversión textual que realizan sus traductores criollos tras la máscara de la fraternidad de los desterrados
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sodium channel br Point of care diagnostic tests POCTs can e
2019-04-23
Point-of-care diagnostic tests (POCTs) can enable health-care workers to provide more rapid and effective care to people in low-resource settings. POCTs should ideally meet the WHO\'s ASSURED criteria—ie, being affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and d
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Se antes Jos Mart em Cuba em com
2019-04-23
Se antes José Martí em Cuba, em 1891, com Nuestra América, e logo, em 1900, José Enrique Rodó com Ariel, propugnavam uma alteridade diversa dos Estados Unidos para os latino-americanos pós-independência, por exemplo, Dipesh Chakrabarty, em Provincializing Europe, reelaborou essas e aquelas consignas
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br La flor de Coleridge En el ensayo
2019-04-23
La flor de Coleridge En el ensayo de ese nombre contenido en Otras inquisiciones leemos: De inmediato, y como corolario de estas ideas, nuestro ensayista da un salto para instalarnos en un mundo donde esta probabilidad se cumple: Como en el universo de Tlön, y siguiendo las premisas del idealis
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br Discussion There are many
2019-04-23
Discussion There are many reports on the effectiveness of pacing therapy for hypertrophic obstructive cardiomyopathy. Fananapazir et al. reported that long-term right ventricular apical pacing improved both the left ventricular outflow tract gradient and subjective symptoms [3]. Maron et al. repo
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The patient received multiagent chemotherapy using cyclophos
2019-04-22
The patient received multiagent chemotherapy using cyclophosphamide, daunorubicin, vincristine, predonisolone and l-asparaginase, and high dose MTX/Ara-C, as well as the single-agent administration of nelarabine, hydroxyurea and tyrosine kinase inhibitors (TKIs) (imatinib and dasatinib). The convent
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In recent years there has been growing
2019-04-22
In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mR
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5-alpha reductase inhibitors br Drug resistance In clinical
2019-04-22
Drug resistance In clinical practice, there is no cross–drug-resistance between As2O3 and RA or other antileukemic agents. This may be explained by the non-liposoluble nature of As2O3, its small molecular weight, and its distinctive modes of action [20]. In our observation, primary As2O3 resistan
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HLA DR resulted highly expressed in the
2019-04-22
HLA-DR resulted highly expressed in the surface of immature DC (iDC) as well as in mature DC (48 h-DC) in both groups; this is possibly due to the chronic infection as previously observed in monocytes-derived DC from HIV+[17]. As expected, maturation and activation markers - CD40, CD80, CD83 and CD8
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As Table shows all guidelines recommend OACs for patients wi
2019-04-22
As Table 2 shows, all guidelines recommend OACs for patients with a CHADS2 score of ≥2, whereas recommendations for low-risk patients with a CHADS2 score of 0/1 differ slightly across guidelines. Evidence indicating that novel OACs decrease the risk of ICH by half as compared with warfarin has affec
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br A KCNJ mutation corresponding to an S L mutation
2019-04-22
A KCNJ8 mutation, corresponding to an S422L mutation in the protein, was first identified in a 14-year-old girl with early repolarization [59], who suffered frequent VF attacks. KCNJ8 encodes Kir6.1, which has 2 transmembrane regions, and the KATP channel is composed of a complex of Kir6.1 or Kir6
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