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CEP-37440 Here we demonstrate that postnatal pituitary SOX
2018-10-24
Here we demonstrate that postnatal pituitary SOX2+ stem CEP-37440 are derived from the embryonic RP and that the Notch signaling pathway is essential for their proliferation, maintenance, and postnatal pituitary expansion. Furthermore, we present evidence that SOX2+ stem cells make a significant co
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In this study we examined the impact of
2018-10-24
In this study, we examined the impact of hormonal signaling on SSC self-renewal using follicle-stimulating hormone β (Fshb; FSH β subunit) and luteinizing hormone/choriogonadotropin receptor (Lhcgr) KO mice. FSH acts on Sertoli inhibitor of catalase within seminiferous tubules, while LHCGR are dete
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TGF-beta Smad Compound Library br Results br Discussion In t
2018-10-24
Results Discussion In this study we have shown that activating BRAF mutations leading to increased RAS/MAPK pathway signaling induce a hypertrophic phenotype in hiPSC-derived CMs. While BRAF-mutant CMs display intrinsic defects in Ca2+ handling, several aspects of their phenotype require parac
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Intriguingly consistent with previous studies Wong
2018-10-24
Intriguingly, consistent with previous studies (Wong et al., 2011; Enver et al., 2005; Haurie et al., 2010), our data show that POLR3G is highly expressed in pluripotent stem proton pump inhibitors and is required for maintenance of the pluripotent state. However, the mechanisms by which how POLR3G
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Fig b shows that the population of the upper
2018-10-24
Fig. 1b shows that the population of the upper sublevel of the 4I11/2 multiplet with the muscle metabolism of 2110 cm−1 does not depend on the rate of relaxation transitions relaxation to the main 4I9/2 level. The calculations proved that in order to adequately model the changes of the emission sp
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One of the significant advantages
2018-10-24
One of the significant advantages of the PDT method is the fact that the photochemical reaction is accompanied by the fluorescence of both the photosensitizer and the singlet oxygen produced as a result of the reaction. The fluorescence analysis allows to perform in situ diagnostics, i.e., directly
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br For an isolated particle n where n is
2018-10-24
For an isolated particle, = = n0, where n0 is the concentration of charged particles in unperturbed plasma; besides, the thickness r0 of the perturbed region for that particle is not known in advance. The charge (the potential) of the particle in the steady-state case is determined by the charge
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Peptone cost The thermal field emission flux becomes substan
2018-10-24
The thermal field emission flux becomes substantial as the surface temperature reaches a certain value, namely The calculations show that the surface roughness reduces the effect of Peptone cost emission, and in fact at a sufficiently high degree of roughness (∼0.8) emission can be neglected ( ≤
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PLX 4032 The problem is reduced to solving the
2018-10-24
The problem is reduced to solving the equilibrium equations in each of the regions:where r and θ are the polar coordinates, \'s are the displacements along the z axis. The perfect contact conditions are imposed: ( are the tangential stresses), along with the conditions along the crack line: where
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br Method br Results Descriptives and bivariate correlations
2018-10-24
Method Results Descriptives and bivariate correlations of all study variables are presented in Table 2, separately for men and women. Tests for the significance of differences between men and women are presented in Table 3. Gender differences were observed for all study variables, except age a
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br Background br Methods br
2018-10-24
Background Methods Results Discussion The hypotheses and whether they were supported are summarized in Table 6. The results indicate that, contrary to prior research on health generally or negative health behaviors such as smoking, own unemployment is not associated with negative changes
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There is at least an implicit
2018-10-24
There is at least an implicit, and possibly quite real, tradeoff between US public spending for medical care versus other social services—for which US spending is a much smaller portion of GDP than in other OECD nations (Avendano and Kawachi, 2014; Stuckler, Basu, & McKee, 2010). This difference rai
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In our previous study we conducted a comprehensive proteomic
2018-10-23
In our previous study, we conducted a comprehensive proteomic analysis to identify candidate biomarkers in OSCC (Wang et al., 2008). Expression levels of 52 proteins in OSCC tumor tissues were significantly different from those in normal tissues (Wang et al., 2009). One of these proteins was PA28γ.
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br Contributors br Declaration of Interests br Acknowledgmen
2018-10-23
Contributors Declaration of Interests Acknowledgments This study was funded by the Fondazione Carlo Denegri, Torino, Italy. We thank all the women who participated in the study. We also thank Daniela Sartori for the assistance in the editing of the manuscript, and Laurene Kelly for the Engl
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br Discussion In this study we demonstrate that
2018-10-23
Discussion In this study, we demonstrate that W ST-11 strains are closely related to serogroup C ST-11 N. meningitidis and likely arose from ancestral capsular switching events. We also demonstrate that the emergence of the Hajj clone in 2000 was caused by a meningococcal strain that was distinc
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