• br Materials and methods br Results br Discussion

  2018-10-22

  

  Materials and methods Results Discussion Obesity results when caloric intake exceeds energy expenditure, with an increase in adipocyte size or adipocyte number (Bjorntorp, 1974; Faust et al., 1978; Johnson et al., 1971, 1978; Yu et al., 1997). In the context of adipogenesis, development app

• The week in vitro culture protocol used in this

  2018-10-22

  

  The 15week in vitro culture protocol used in this study provided a very challenging culture system to examine long term potential of the cell sources. When grown in a large 6mm×9mm PCL scaffold, the AFS SC 144 had great potential but the cells required an extensive induction time prior to their ost

• br Correlations between gene expression and immunophenotypin

  2018-10-22

  

  Correlations between gene expression and immunophenotyping Whilst there is no guarantee of a direct correlation between mRNA levels and protein, as not all mRNA is present at the translational machinery and different cell surface proteins show different rates of delivery to and recycling from the

• We derived ESC lines from

  2018-10-22

  

  We derived ESC lines from blastocysts of the double transgenic mouse line Mlc2v-Cre; Rosa26-Yfp, in which Cre and Yfp are specifically knocked into the Mlc2v and Rosa26 gene loci, respectively. Mlc2v-Cre-mediated removal of a stop sequence in the Rosa26-YFP reporter line results in expression of YFP

• Mammalian mitochondria are composed of approximately differe

  2018-10-22

  

  Mammalian mitochondria are composed of approximately 1000 different proteins, but only 13 proteins are encoded by the mitochondrial genome. We selected Atp5g, Atp8 and Ucp2 as protein markers of the mitochondrial genome. We observed progressively higher expression of Ucp2, Atp5g and Atp8 in hiPSCs,

• Similar to our observation that Nanog

  2018-10-22

  

  Similar to our observation that Nanog−/− iPSCs could give rise to chimeric animals, Nanog null ESCs have been shown to contribute to the three germ layers (Chambers et al., 2007). However, in the case of ESC chimeras, Nanog−/− GFP+ K03861 were not detected in the germline after E12.5. Because the C

• br Introduction Epidermal stem cells SCs are

  2018-10-22

  

  Introduction Epidermal stem Phenyl sulfate (SCs) are localized in several well-defined cellular compartments with the best-studied being an anatomical area of the hair follicle (HF) known as “bulge” (Blanpain and Fuchs, 2009; Cotsarelis et al., 1990; Jaks et al., 2010). This unique anatomical sit

• We found seven published clinical trials

  2018-10-22

  

  We found seven published clinical trials studying the effects of MSC transplantation in patients with liver cirrhosis (listed in Table 2). A pilot phase 1 study published in 2007 included four patients with decompensated liver cirrhosis (Mohamadnejad et al., 2007). Cells were derived from iliac cres

• Because SAPK mediates hyperosmolar stress induced

  2018-10-20

  

  Because SAPK mediates hyperosmolar stress-induced Hand1 and Hand1-dependent PL1 (Awonuga et al., 2011), we tested whether stress-induced lineage choice during hypoxia was SAPK-dependent. Since hyperosmolar stress induces the first lineage but not later lineages from TSC (Liu et al., 2009), and SAPK

• SCR 7 manufacturer The myocardium lacks the basal apical ori

  2018-10-20

  

  The myocardium lacks the basal–apical orientation typical of epithelial organs making it difficult to delineate the precise localization of CSC niches. The epicardial lining has been employed to define anatomically several classes of niches in the adult heart (Castaldo et al., 2008; Di Meglio et al.

• Recapitulating developmental signaling pathways in different

  2018-10-20

  

  Recapitulating developmental signaling pathways in differentiated cardiomyocytes has the potential to stimulate proliferation. Under this premise, developmental signaling pathways should be present in differentiated cardiomyocytes and available for activation. For example, developmentally expressed

• br Materials and methods br Results br Discussion The use

  2018-10-20

  

  Materials and methods Results Discussion The use of hNPCs for disease modeling, drug screening, or cell therapies requires the development of efficacious and cost-effective defined substrates for their expansion and neuronal differentiation. In this study, we employed an unbiased, high-thro

• One most recent study first reported the feasibility of usin

  2018-10-20

  

  One most recent study first reported the feasibility of using undifferentiated hPSC 69 9 for cardiac differentiation in suspension by small molecules modulating Wnt pathway (Kempf et al., 2014). With a fixed differentiation condition without controlling cell aggregate size, the authors show cardiac

• pppa After comparing the lymph angiogenic effects

  2018-10-20

  

  After comparing the (lymph)angiogenic effects of HLE and HLF, UVB-induced changes in their protein expression patterns were also assessed. As shown by the protein array assessment, following UVB irradiation of HLF pppa amphiregulin, uPA (a strong promoter of angiogenesis (Oh et al., 2003) the expres

• Immunohistochemical studies revealed increase in the proport

  2018-10-20

  

  Immunohistochemical studies revealed increase in the proportion of CD44highCD24low cell type from low in normal tissues to quite high in tumours. This is interesting as we know that Cancer Stem Cells are the actual tumour initiating subpopulation and can expand depending on its evolutionary landscap

16649 records 1109/1110 page Previous Next First page 上5页 11061107110811091110